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Haematologic Technologies, Inc.

57 River Road

Essex Junction, VT USA

Tel: 802.878.1777

Fax: 802.878.1776

Email: hti@haemtech.com

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Snake venom proteases are useful tools for studying coagulation reactions.  The venom proteases offered are highly purified, homogenous preparations with the indicated activities.  All of our venom products are supplied in 50% glycerol for storage at -20oC.

RVV-V ACTIVATOR RVV-X ACTIVATOR ECV- PROTHROMBIN ACTIVATOR

CATALOG #

 RVVV-2000 RVVX-2010 ECVII-2011

SOURCE

 Vipera Russelli Russelli Vipera Russelli Russelli Vipera Echis 

Carinatus

MOLECULAR WEIGHT

 Mr = 27,200 single chain glycoprotein Mr = 79,000 glycoprotein 2 disulfide linked subunits 

(Mr = 67kD, 26kD)

 Mr = 56,000 

single chain

CLASS

serine protease

Zn+2 dependant endopeptidase

metalendo-

peptidase

INHIBITORS

DFP

EDTA, o-phenanthroline

EDTA, DTT

o-phenanthroline

APPLICATION

converts single chain factor V to an active two chain form

Conversion of factor X to Xa, factor IX to IXaα

Cleavage of Arg332-Ile323 

bond in 

prothrombin to 

form meizothrombin

Catalog Number

 Description

RVVV-2000

 RVV-V Activator

RVVX-2010

 RVV-X Activator

ECVII-2010

 ECV-Prothrombin Activator

PRICING

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References 

  1. Kisiel, W., et.al., Biochen., 15, 4901-4905 (1976).
  2. Kisiel, W. and Canfield, R., Meth.Enzymol., 80, 275-285 (1980).
  3. Kane, W. and Majerus, P.J., J.Biol.Chem., 256, 1002-1007 (1987).
  4. Morita, T. and Iwanaga, S., Meth.Enzymol., 80, 303-311 (1980).

 Please inquire about products not listed.  We can also custom purify proteins from other species. 

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